At least eight migrants drowned while 37 were rescued while attempting to cross Rio Grande river to reach the United States, officials have said.
US officials recovered six bodies, while Mexican teams found two others, CBP said in a statement.
Moreover, US officials detained 53 migrants, while Mexican officials took 39 into custody.
So far it is unclear as to which country or countries the migrants belonged to as the officials did not provide any additional information
The migrants were among scores of people crossing the river near Eagle Pass, a town in southern Texas that has become a major entry point for migrants in the last year, reports The New York Times.
US Customs and Border Protection (CBP) and Mexican officials said they found a large group of people unconscious after attempting to cross the swollen river following days of heavy rains. Officials from both sides said that they are searching for any possible victims.
The Del Rio region, including Eagle pass, sees a hub of illegal crossings and is fast emerging to be the busiest corridor for human trafficking.
Crossing the Río Grande river, which extends 245 miles (395 kilometres), has been considered dangerous because river currents can be deceptively fast and change quickly. Crossing the river can be challenging even for strong swimmers.
So far, the officials have thwarted migrants nearly 50,000 times in the sector in July, with Rio Grande Valley a distant second at about 35,000. About 6 of 10 illegal crossings were migrants from Venezuela, Cuba or Nicaragua, according to reports.